This lysergic looking advertisement for Brown’s Iron Bitters appeared in the October 2, 1884 edition of The Chatham Record with these words in bold type:
Brown’s Iron Bitters combines Iron with pure vegetable tonics. It is compounded on thoroughly scientific and medicinal principles, and cannot intoxicate.
On the other hand, many of the resources I visited to learn more about Brown’s Iron Bitters led with this sentence: “This product contained cocaine.”
Maybe it was hard to tell, given that it was delivered in 39% alcohol.